Postdoc Position in Chromatin Neurobiology

Postdoctoral position is available in the Iwase laboratory (https://www.brainchromatindynamics.com/) at the University of Michigan Medical School, Department of Human Genetics.

Candidate is expected to determine molecular mechanisms underlying Smith-Magenis Syndrome (SMS). SMS is caused by mutations of RAI1 a putative histone binding protein. Candidate will be able to use chromatin biochemistry, functional genomics, and mouse models to explore the roles of RAI1 in brain development, circadian rhythm and synaptic plasticity. Ultimate goal of the project is to develop therapeutic strategies for SMS.

The salary range: $48,000 ~ $55,000 per year, plus a competitive benefits package. Candidate will have an opportunity to supervise one or more undergraduate students. The appointment of this position is at least 1 year and the appointment will be renewed in yearly basis. The position is supported by private foundation of an SMS patient family. The University of Michigan Medical School is a largest biomedical research enterprise located in Ann Arbor, one of the safest and most educated cities of the United States.

We are looking for highly-motivated individual who meets the qualification below
• Strong experience and skill sets in molecular genetics and biochemistry.
• Ph.D. in molecular genetics and biochemistry-related disciplines.
• Excellent oral and written communication skills.
• Experiences in one or more of the following fields preferred, but not required: Neurobiology, mouse genetics, and bioinformatics.
• Commitment for long-term research on molecular neurobiology of SMS and related disorders.

Qualified candidates are invited to send the following materials to siwase@umich.edu
• Cover letter outlining current research efforts and motivation to apply for this position.
• Curriculum vitae.

Publication from the laboratory
http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/49720759/?sort=date&direction=descending

More recent manuscripts under revision
https://www.biorxiv.org/content/10.1101/523456v1
https://www.biorxiv.org/content/10.1101/567917v2
https://www.biorxiv.org/content/10.1101/175174v1
https://www.biorxiv.org/content/10.1101/146357v2