Postdoc Positon Available (Case Western Reserve University, Department of Pharmacology)

A postdoctoral position is now available in the Department of Pharmacology in the School of Medicine at Case Western Reserve University. The laboratory is currently funded by the NIH and a private foundation that focuses on Usher Syndrome. Our research focus is retinal cell biology with the goal of discovering small molecule therapy for photoreceptor degenerative disorders. To elucidate the disease mechanisms, we genetically dissect the process of photoreceptor morphogenesis and maintenance in vertebrate animals. Our laboratory pioneered real-time imaging of proteins and small molecules within the retina, and takes advantage of state of the art confocal/multiphoton/STED microscopy techniques. Our research also heavily depends on the tissue culture system to biochemically study the components required for photoreceptor morphogenesis/maintenance. For more details, check our website: https://www.imanishi-lab.org

The applicant is expected to be highly independent and be capable of designing experiments and conducting hypothesis-based research projects. The candidate should have a strong background in cell biology, molecular biology, or biochemistry. Knowledge of fluorescence microscopy is favorable, although not necessary. Salary will be commensurate with experience and will adhere to current NIH guidelines.

Please submit your CV, brief statement of research interest, and contact information for three references via E-mail to Dr. Yoshikazu Imanishi (yxi19@case.edu).

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【Boston】 医師・Medical・Pharmaceutical・Science Career 交流会
【Date/Time】　2018年7月27日（金）
19:00-20:00 Presentation/ Q&A, 20:00-21:00 Networking（途中参加・途中退席可）
【Location】　Sheraton Boston Hotel
【Company】Johnson & Johnson
【対象者】　Area: Medical, Pharmaceutical, Scienceに携わっていらっしゃる方
Degree: Masters, PhDs, Postdocs
【詳細】　https://www.business-paradigm.com/bpc/doctors_jj.html
*当日のご都合が合わない方は、別の日に個別対応も可能です。お気軽にお問い合わせください。

【お申込み・ご質問】参加費用は無料ですが、事前予約が必要です。お早めに下記担当者まで、ご連絡いただけると助かります。
Ms Hirotsuna career@business-paradigm.com
1)　お名前
2)　所属先名称　（学生の場合は、学校名・年次。）
3） 医師免許可否
4) 電話番号　

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Postdoctoral Fellow Position
Job description
Postdoctoral fellow positions are available for candidates with previous experience in mouse models relevant to human diseases, especially cardiac disease. We are looking for applicants with strong research background in transcriptional regulation/signaling pathways/non-coding RNAs using multiple experimental techniques including cell culture, RNA analysis, chromatin immunoprecipitation, performing mouse breeding, genotyping, and routine experiments such as cloning, Western blot, immunoprecipitation and immunohistochemistry analyses.
The PI has been funded by NIH & AHA grants. All eligible trainees have been also awarded AHA fellowships. Please visit the webpages below for his lab information, his detailed research interest, and his publications:
http://www.augusta.edu/centers/vbc/kim.php
http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/43848679/?sort=date&direction=++++++ascending.
https://augusta.pure.elsevier.com/en/persons/il-man-kim/publications/
Salary will be commensurate with qualification and experience. Preferred candidates would be recent graduates or within 3 years of postdoc training who are eager to apply postdoc fellowships and/or next career levels of grants such as AHA CDA or NIH K awards. Interested candidates should apply by emailing their CVs along with any supporting documents.
Review of applications will begin immediately. The positions are open until offers are accepted.
For further information, please feel free to contact the PI below.
Sincerely,
Il-man Kim, Ph.D. Associate Professor with Tenure
Vascular Biology Center
Department of Biochemistry & Molecular Biology
Medical College of Georgia
College of Graduate School
Augusta University
Office: CB-3717
Phone: (706) 721-9414
FAX: (706) 721-9799
Email: ilkim@augusta.edu

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Postdoctoral Research Fellow in the Cell Cycle in Development Laboratory (Kimata group).

The ‘Cell Cycle in Development’ Laboratory (PI: Dr Yuu Kimata) is moving from the University of Cambridge to open a new laboratory at the School of Life Science and Technology (SLST) at the ShanghaiTech University in Shanghai, China.

We are looking for an ambitious, highly-driven postdoctoral scientist to work with Dr Kimata to elucidate the functions of the cell cycle-regulating
proteins in coupling cell cycle exit to cell fate determination and cellular
differentiation during the metazoan development.

The Kimata lab aims to understand the molecular and cellular mechanisms by which the cell cycle is coordinated with developmental and homeostatic processes in the metazoan organism. We combine the model systems of Drosophila melanogaster and mammalian organoids with in vitro cell culture, biochemistry, proteomics and bioinformatics, and have been working with international collaborators including David Glover, Marc de la Roche(University of Cambridge), Renata Basto (Curie Institute), and Hiroyuki Yamano (UCL).

The focus of our research has been on the evolutionarily conserved multisubunit ubiquitin ligase, the anaphase promoting complex/cyclosome (APC/C). We have recently discovered:
1) APC/C regulates the transcriptional activity of one of the major extracellular signalling pathways, the Wnt signalling pathway, during the retinal development in Drosophila (Martins et al., 2017 Developmental Cell);
2) APC/C ensures cell fate determination of the neural stem cell and the oocyte through the regulation of the centrosome (Meghini et al., 2016, Nature Communications, Braun et al., bioRxiv).
For further information of our research, please visit the Kimata lab websites:
https://www.gen.cam.ac.uk/research-groups/kimata (University of Cambridge), or, http://www.kimatalab.com/ (the lab’s own website).

The joined researcher will address fundamental biological questions centring around the cell cycle control in the multicellular organism such as:
• How are cell cycle exit and cellular differentiation coupled, and what are the role of cell cycle-regulating proteins in this coupling?
• How are these coupling mechanisms or the uncoupling of these processes involved in human disease?
• How is cell proliferation regulated in vivo, and how can it be controlled at will?
The specific projects for the researcher will be determined through discussions with Dr Kimata, depending on their skills and experience as well as the availability and the timeliness of the projects.

The successful candidate will have a strong track record and will demonstrate excellent interpersonal, organisational and time management skills and good English communication skills. An individual with a strong passion for science and collaborative and can-do attitudes will best fit to our lab. Applications from adventurous foreign individuals are also highly encouraged.

The research will be based in the modern open lab space in the SLST in ShanghaiTech University, situated in the heart of Zhangjiang Hi-Tech Park in the Pudong Science District in Shanghai. The initial term of this post is 24 months, but the term can be extended up to 4 years, with the possibility of the promotion to Research Assistant Professor. The annual salary will be decided based on the University salary scale, and the experience and qualification of the candidate. The typical salary for a newly graduated postdoc is 155,000 RMB. All postdocs in ShanghaiTech will have access to various social benefits provided by the university, including an on-campus accommodation and a contribution to the social security.

The detailed job description and the instruction of the application process are described below. Any informal enquiries regarding the role and the research project should be directed to Dr Kimata via e-mail: yk299@cam.ac.uk.

Key Responsibilities:
• To design the course of research projects under the guidance of Dr Kimata.
• To design experiments and conduct them accurately and reproducibly.
• To analyse and interpret data objectively and critically.
• To report and discuss results with Dr Kimata and other lab members.
• To present the work at internal and external seminars and at national and
international scientific conferences.
• To contribute to the preparation of publications and applications for funding.
• To assist Dr Kimata with the supervision of students and/or junior research staff working in support of the projects.
• To cooperate with Dr Kimata and lab members in organising lab reagents and
equipment and in maintaining a high standard of the lab space.

Person’s profile:
Education & qualifications • A PhD or an equivalent degree in a biomedical science.
Scientific knowledge and skills (essential):
• Basic knowledge in molecular cell biology, genetics, developmental
biology, bioinformatics and statistics.
• Logical thinking and critical thinking.
• Experience and skills in molecular cell biology or biochemical
experiments.
• Experience and skills in microscopy and quantitative image analysis.

Specialised knowledge & skills (desirable):
• Knowledge of Drosophila biology and methodology.
• Knowledge of developmental biology and/or the cell cycle research.
• Experience and skills in experiments using Drosophila.
• Experience in confocal and light microscopy.
• Experience in any of the following areas: cell culture, mammalian
organoid culture, biochemistry, advanced microscopic techniques
super-resolution microscopy, EM), bioinformatics/statistics.

Interpersonal & communication skills (essential):
• Ability to present and discuss the work and research topics clearly in
written and spoken English with the supervisor and academic coworkers.
• Ability to cooperate with and support colleagues and to maintain
cohesive and collaborative relationships.

Relevant experience & skills (desirable):
• Publications in the scientific literature
• Experience in presenting at international conferences
• Experience in supervising students or junior colleagues
• Experience in communicating and collaborating with scientists in relevant or different disciplines.

Application process:
Qualified applicants are requested to provide the following items (in English):
1. A cover letter describing your interests and professional goals
2. Curriculum Vitae including academic background and work experience
3. List of publications and PDF files of three best papers (if applicable)
4. Contact details of two or three referees, one of which must be your most recent supervisor/line manager. References will be requested after the initial selection.

Applicants who are interested in this position should submit the above documents directly to Dr Yuu Kimata via e-mail: yk299@cam.ac.uk. At the same time, applicants should also complete the online application form using the Shanghai University of Science and Technology Talent Recruitment System ( http://jobs.shanghaitech.edu.cn/ ) following the instruction. Shortlisted candidates will be contacted and interviewed by Dr Kimata.

The formal selection process will commence after 30th June 2018 and will continue until the
position is filled.

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Research Fellow position at Kyushu University Hospital

A Research Fellow position is available in the laboratory of Takahiro Maeda, M.D., Ph.D. at Kyushu University Hospital. Our laboratory uses gene editing and molecular/cellular biological techniques to elucidate the molecular basis of the globin switch and to develop novel therapeutics for sickle cell disease (SCD).

1. Canver MC et al. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature. 2015 Nov 12;527(7577):192-7. PMID: 26375006.
2. Masuda T et al. Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin. Science. 2016 Jan 15;351(6270):285-9. PMID: 26816381.
3. Yamauchi T et al. Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS enzyme. Cancer Cell. 2018 Feb 8. pii: S1535-6108(18)30012-6. PMID: 29478914

The applicant must have a Ph.D. or M.D. degree and one or more first author publications in peer reviewed journals. Recent graduates are particularly encouraged to apply. We are looking for enthusiastic, self-motivated individuals who thrive in a fast-paced environment and can interact well with others as part of a team. The applicant should also have a strong background in biochemistry and molecular biology. Please send curriculum vitae, a brief statement of interest, and names of three references (with contact information) to t_maeda@cancer.med.kyushu-u.ac.jp

Takahiro Maeda M.D., Ph.D.
Associate Professor Center for Cellular and Molecular Medicine
Kyushu University Hospital
3-1-1 Maidashi, Higashi-ku, Fukuoka, Fukuoka 812-8582, Japan
Phone: +81-92-642-5948
Fax: +81-92-642-5951
Email: t_maeda@cancer.med.kyushu-u.ac.jp

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ポスドク募集; Boychuk Lab, UT Health San Antonio

私（Teppei Fujikawa, Ph.D.)が所属するテキサス大学ヘルスサンアントニオ校(以下UTHSA) で共同研究者であるDr. Carie R. Boychukがポスドクを一名募集しています。Dr. Boychukのかわりに私が投稿させて頂いています。詳細は下記に書いてありますが、中枢神経系での電気生理の経験を持つ方を探しています。Boychuckラボと当ラボ（Fujikawa Lab)は共同プロジェクトを立ち上げて密接に連携しています。Boychuk Labでは電気生理の技術を中心に、生体における代謝調節機構を性差やさまざまな観点から研究しています。特に副交感神経系による代謝調節機構に着目して現在研究を行っています。興味のある方はぜひDr. Boychuk(boychukc@uthscsa.edu)にご連絡ください。

以下は僕からサンアントニオに関する情報です。

サンアントニオはテキサス州では人口が2番目に大きな都市であり(全米で7位)、今アメリカで経済的に最も成長している都市の一つです(https://www.brookings.edu/wp-content/ uploads/2016/07/MetroMonitor.pdf)。ボストンやカルフォルニアに比べると娯楽や日系スー パーなどは無いですが、物価は安く賃貸の値段も沿岸部、さらには同じテキサス州の大都市で あるダラス、ヒューストン、オースティン等と比べても圧倒的に安いです(https://www.apartmentlist.com/rentonomics/december-2015-texas-apartment-list-rent-report/)。またテキサスは州税が無いです。その為ポスドクの給与でも余裕をもって生活はできますし、研 究に集中して望める環境です。また日本人補習校がある事からわかるように一定数の日本人も 居ます。アメリカに来て以来テキサスのみで過ごしていますが、非常に生活しやすいと思いま す。気候的には夏は40度近くになることもしばしばありますが、湿気が少ない分日本の夏よりずっと過ごしやすいです。

UTHSAは研究大学院で特にPhysiologyおよびAgingの研究で有名です。我々のDepartmentは Neuroscienceを軸として様々なバックグランドの研究者が所属しており、多くのコラボレー ションがあります。

質問等がありましたらCarie(boychukc@uthscsa.edu)もしくは私に(fujikawa@uthscsa.edu) メールを頂ければと思います。

以下募集詳細です。
--------------------------------------
One postdoctoral fellow position is immediately available in the laboratory of Dr. Carie R. Boychuk in the Department of Cellular and Integrative Physiology at UT Health San Antonio (http://physiology.uthscsa.edu/). Candidates should be interested in investigating the synaptic mechanism(s) by which vagal motor output regulates peripheral organ function.
The Boychuk Lab focuses on 1) the role of vagal motor output in the regulation of glucose homeostasis and the autonomic complications that can arise when this system is dysregulated and 2) the influence of reproductive hormones on that regulation of vagal output. To address these issues, we use physiological testing, brain micromanipulations, electrophysiology, and molecular biology.
All postdoctoral appointments are designated as security sensitive positions.
The UT Health San Antonio is an Equal Employment Opportunity/Affirmative Action Employer, including protected veterans and persons with disabilities.

We are looking for highly motivated and enthusiastic talent. The candidate should have excellent communication skills, be self-motivated, a quick-learner, and importantly a team player. Candidates should have experience with electrophysiology and experience working with mice or rats is preferred. Minimum requirements are Ph.D. or M.D.. Applicants who anticipate to defend their thesis in the near future are also encouraged to apply.
For more information:https://physiology.uthscsa.edu/team-member/carie-r-boychuk-ph-d/ Please send following documents as combined single PDF to Dr. Carie Boychuk (boychukc@uthscsa.edu).
1) CV including education list, publication list and at least three names and email addresses of references
2) Summary of previous and current research including a future career plan (1-2 pages)

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研究室員を募集させていただきます。(日本語版は下にあります）

Research positions available (computational biologist, bioinformatician, pathologist, anatomic pathologist, diagnostic pathologist, other experts can be considered)

I am seeking candidates for research positions (pathologist, computational biologist, and/or bioinformatician) in my laboratory at Dana-Farber Cancer Institute (DFCI), Brigham and Women's Hospital (BWH), the Broad Institute of MIT and Harvard, Harvard T.H. Chan School of Public Health, and Harvard Medical School, in the Boston area, MA, USA. Salary can be offered if a candidate has specific skills and expertise (such as Pathology, Computational Biology, and Bioinformatics). Candidates in other areas can be considered; other areas include epidemiology, biostatistics, molecular biology, immunology, microbiology, and clinical medicine. Candidates with funding support will be highly considered, but candidates without funding will also be considered.

My laboratory is The Molecular Pathological Epidemiology (MPE) Laboratory, which is a very unique, interdisciplinary multi-institutional laboratory. I have been selected to receive 7-year funding of the Outstanding Investigator Award (OIA) from NIH/NCI (2015-2022; http://grantome.com/grant/NIH/R35-CA197735-01). I established an integrative science of MPE (Ogino et al. J Natl Cancer Inst 2010; Ogino et al. Nat Rev Clin Oncol 2011; Ogino et al. Lancet 2018; etc), and have been making the history of MPE. I have been organizing the International MPE Meeting Series (www.mpemeeting.org). My MPE lab has been working on not only gastrointestinal cancers but also methods that can be used in many different areas. We have been developing new scientific frontiers such as “immunology-MPE”, “pharmaco-MPE”, “microbiology-MPE”, MPE method development, and integration of MPE and other areas such as causal inference, health communication, and com!
parative effectiveness research. For more information, please visit these links.
http://ogino-mpe-lab.dana-farber.org/
http://www.hsph.harvard.edu/faculty/shuji-ogino/
www.mpemeeting.org

Please email me (shuji_ogino@dfci.harvard.edu) your CV or any inquiry. Please pass this information to anyone who may be interested. Please note that I may not be able to reply to all inquiries.

Selected original and concept papers:

X Liao et al. NEJM 2012; R Nishihara et al. NEJM 2013; AT Chan et al. NEJM 2007; E Barry et al. Nature 2013; R Straussman et al. Nature 2012; M Giannakis et al. Nat Genet 2014; R Nishihara et al. JAMA 2013; T Morikawa et al. JAMA 2011; AT Chan et al. JAMA 2009; K Nosho et al. Gastroenterology 2009; K Nosho et al. J Pathol 2010; S Fink et al. Sci Transl Med 2014; ZR Qian et al. J Clin Oncol 2013; A Kostic et al. Genome Res 2012; M Song et al. JNCI 2015; K Inamura et al. JNCI 2014; P Lochhead et al. JNCI 2013; S Ogino et al. JNCI 2013; A Kuchiba et al. JNCI 2012; M Song et al. Gut 2016; M Yamauchi et al. Gut 2012; M Giannakis et al. Nat Genet 2014; K Mima et al. Cancer Immunol Res 2015; K Mima et al. JAMA Oncol 2015; K Inamura et al. JNCI 2016; K Mima et al. Gut 2016; M Song et al. JAMA Oncol 2016; M Giannakis et al. Cell Reports 2016; Y Cao et al. Gastroenterology 2016; R Mehta et al. JAMA Oncol 2017; T Hamada et al. J Clin Oncol 2017; R Mehta et al. Gastroenterology 2017; S !
Bullman et al. Science 2017; Grasso et al. Cancer Discov 2018; Ogino et al. Gut 2018; Ogino et al. Lancet 2018.

研究室員の募集

ボストンにある私のThe Molecular Pathological Epidemiology （MPE) Laboratory分子病理疫学研究室で研究室員（computational biologist, bioinformatician， pathologist, anatomic pathologist, diagnostic pathologist　あるいは他の分野）を募集しています。私のＭＰＥ研究室は中心はDana-Farber Cancer Instituteに位置しながらハーバード大学関連のいくつかの施設（Dana-Farber Cancer Institute, Brigham and Women's Hospital, the Broad Institute of MIT and Harvard, Harvard T.H. Chan School of Public Health, and Harvard Medical School）にまたがって存在し、機能しています（従来のラボの概念を超越しています）。私は日本人で現在唯一のNCI R35 Outstanding Investigator Award (OIA) Grant 保持者のようです(http://grantome.com/grant/NIH/R35-CA197735-01）。ポジションとしては常任研究員、ポスドクのいずれかが可能です。経験、能力（特にPathology, Computational biology/bioinformaticsの能力）に応じて、自前のグラントなしでも給与のサポートすることも可能です。自前のグラント（フェローシップ等)サポートがありますと、ポジションをオファーする可能性が高まります。Epidemiology、Biostatistics、Molecular Biology、Immunology, Microbiology, 臨床医学のbackgroundを持つ方も考慮しており、得意な分野・経験を生かしていただきます。プロジェクトは消化器腫瘍を使ってMolecular Pathological Epidemiology (MPE、分子病理疫学)、Immuno-MPE（免疫分子病理疫学）、Pharmaco-MPE (薬理分子病理疫学)、 Microbiology-MPE（微生物分子病理疫学）、病気を限定しないMPE解析手法の開発、あるいはMPEと他の分野とのあらたな統合分野の設立と多岐にわたります。ラボメンバーのCareer Developmentのサポートも充実しています（このリンクをご覧ください　http://uja-info.org/findingourway/post/1484/)。　これまで40人以上のポスドクが栄転していきました。私の指導のもとで、人にもよりますが、2年間の研究留学で、筆頭著者でおよそ２－5本の高質の論文を出した人が多数いますし、Co-First Authorship 制度をとってポスドクの成果をより大きくしています。

MPEは私が創造した学問分野で、その名が示すとおり、分子病理学と疫学の統合という新しい学問分野です（Ogino et al. JNCI 2010; Ogino et al. Nat Rev Clin Oncol 2011; Ogino et al. Lancet 2018; etc)。私は2013年に国際分子病理疫学学会を設立し、第5回国際分子病理疫学学会を2020年6月に計画中です(www.mpemeeting.org)。このように分子病理疫学の歴史を作っています。

近年の主要プロジェクトとしては、大腸癌をモデルとして、癌と免疫システムの相互作用への、環境因子や微生物因子の影響を、大規模集団とデータベースを駆使して調べています。この分野を免疫分子病理疫学（Immuno-MPE,　Immunology-MPE）として設立し、その分野の先頭を走っています。この分野は免疫療法 (Immunotherapy)、免疫予防 (Immunoprevention) に寄与するものと期待されています。Computational biologyとBioinformaticsの手法を使って、免疫分子病理疫学をさらに発展させるのも重要プロジェクトです。

我々のMPE　Researchの強みは最近のさまざまな論文で示されています(上に主要な論文を列挙しました)。分子病理疫学と私の研究室についてはこれらのサイトをご覧ください。
http://ogino-mpe-lab.dana-farber.org/
http://www.hsph.harvard.edu/faculty/shuji-ogino/
www.mpemeeting.org

興味のある方は（shuji_ogino@dfci.harvard.edu）宛てにCVをつけて直接連絡をお願いします。興味のありそうな人をご存知の方は、この情報をパスして頂きますと幸いです。お問い合わせや応募が多い場合は返答しきれないことがありますが、ご容赦ください。
荻野周史
Shuji Ogino, MD, PhD, MS

Chief, Program in MPE Molecular Pathological Epidemiology at Brigham and Women’s Hospital

Professor of Pathology at Harvard Medical School, Brigham and Women’s Hospital, and Dana-Farber Cancer Institute

Professor (Epidemiology) at Harvard T.H. Chan School of Public Health

Associate Member at Broad Institute of MIT and Harvard

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2018年9月より米国のペンシルバニア大学（獣医学部と医学部病理部門兼任）にて研究室を主催するにあたり、研究室の立ち上げに関わってくださる研究員(ポスドク）の募集を行います。生殖医療・生殖工学、発生学、幹細胞学、特にバイオインフォマティクスなどの知識と経験のある博士号取得（見込）者が望ましいですが、熱意のある優秀な方であれば分野や技術は問いません。

研究テーマとして、ヒト生殖細胞（特に雄性生殖細胞）と生殖腺の発生学とその試験管内再構成系の確立を大きな目標とします。

シングルセル解析法を用いた胎生期のヒト生殖細胞の遺伝子発現解析、メタボローム解析、エピゲノムや3Dゲノム解析、ヒト生殖腺の初期形成機構や性分化機構の包括的理解を目的とした形態学的解析およびシングルセル解析、ヒトiPS細胞を用いたヒト生殖細胞や生殖腺体細胞の分化誘導などを予定しています。

発生学はモデル動物を中心に発展してきましたが、近年のシングルセルゲノミクスやゲノム編集技術を駆使することにより今までほとんど解析がなされてこなかったヒト胚発生に対するより直接的な分子生物学的アプローチが可能となってきています。ヒト胚のin vivo解析と併せてヒトiPS細胞を起点とした生殖細胞と生殖腺体細胞の試験管誘導を行うことで、確固とした基盤の上に、次世代の生殖・再生医療に直結する研究を行います。

ペンシルバニア大学は米国屈指の名門校であるアイビーリーグのひとつとして知られており、大変充実した研究施設や共同研究体制が整備されており、優れた研究環境を提供できます。ペンシルバニア大学に隣接する全米最大のペンシルバニア小児病院 (CHOP)やペンシルバニア大学病院から非常に豊富な臨床サンプルが入手可能であり、性分化疾患や胚細胞腫瘍・性腺腫瘍などのサンプルを用いた研究も行う予定です。　またフィラデルフィアは全米で5位の人口を有する大都市ですが、ニューヨークやサンフランシスコなどに比べ、物価が比較的安く、治安もよい住みやすい町として知られています。

待遇：応募者の経験ならびにNIHの規定に準じる
採用時期：2018年9月以降　最低2－3年は研究を継続できる方を希望
応募人数：1人
募集期間：適任者が決まり次第締め切り

ご希望の方はCVと2名の推薦者の連絡先を添付の上、下記までemailにてご連絡ください。また、質問等がありましたら、遠慮無くご連絡ください。

Kotaro Sasaki, M.D., Ph.D.
Assistant Professor, Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine

School of Veterinary Medicine, University of Pennsylvania
3800 Spruce Street, Old Quad Room 220E, Philadelphia PA 19104
Email: ksasaki@vet.upenn.edu

[参考文献]
1. Cell Stem Cell. 2015 Aug 6;17(2):178-94. Robust In Vitro
Induction of Human Germ Cell Fate from Pluripotent Stem Cells.
2. Dev Cell. 2016 Oct 24;39(2):169-185. The Germ Cell Fate of
Cynomolgus Monkeys Is Specified in the Nascent Amnion.

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博士研究員および技術員の募集
テキサス大学 (The University of Texas Health Science Center at Houston)

テキサス大学 (The University of Texas Health Science Center at Houston) の岩田研究室では、 研究員およびテクニシャンを１名ずつ募集しております。

当研究室では、膜輸送と細胞内代謝の機構を精力的に研究しております。特に、頭蓋や顔面（口蓋、筋肉、唾液腺、歯など）の発生や疾患過程を遺伝子改変マウスを使って解析しています。マウスを使った実験の経験があり、やる気と協調性を持って仕事のできる方を求めています。留学中にしっかりした仕事をしたい人は是非アプライしてください。その後のキャリアについても最大限のサポートをします。

ヒューストン医療センターは世界屈指の規模を誇り、街の治安も非常によいことから、研究と居住の両方において理想的な環境です。日本食材も容易に手に入りますし、日本語補習校の規模も大きく、日本人コミュニティーもしっかりしています。研究者間のコラボレーションやセミナーも多く、非常に充実した研究環境で仕事ができます。なお、生活準備のサポートもしますので、はじめての海外生活の方も安心して生活がはじめられると思います。

研究内容：組織学的手法、生化学的手法、分子生物学的手法を組み合わせて仕事を進めていきます。日本で研究に没頭していた人で、海外留学を機にもっとチャレンジをしてみたい人にはいろいろなテーマに関わるチャンスがあります。

応募資格：組織学的解析あるいは細胞を使った実験手技のいずれかを十分に取得されている方を希望しています。遺伝子改変マウスの解析経験や知識があることが望ましいです。ただし、日本で基礎研究に従事していた方であれば、こちらでの仕事にもすぐに馴染めると思います。

着任時期：出来るだけ早い時期（応相談）

任期：１年から

待遇： テキサス大学の規定による。

応募書類：興味のある方は、英文の履歴書（大学以降の学歴および職歴、論文リスト、実験技術、３名の推薦者の連絡先）をJunichi.Iwata@uth.tmc.eduまで、Emailで送ってください。

岩田　淳一
Junichi Iwata, DDS, PhD
Email: Junichi.Iwata@uth.tmc.edu

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Postdoctoral Research Fellow at the University of Michigan

Job Summary
The Seo lab at the University of Michigan seeks a postdoctoral research fellow for a 2-year NIH-funded position (with possible extension) to study cell and molecular biology of metals with relevance to metabolic and neurological diseases. The Salary range: $48,000 ~ $55,000 per year, plus a competitive benefits package and the opportunity to appoint and supervise one or more paid undergraduate to work on projects of your choice.

Required Qualifications
We are looking for a highly-motivated individual who meets the qualification below.
• PhD in molecular and cell biology/biochemistry/genetics/neuroscience or related discipline.
• Experience with knockout, Crispr/Cas9, and transgenic mice.
• Excellent oral and written communication skills.
Desired Qualifications*
• Publications demonstrating research experience and productivity.
• Preferably within the first two years of receiving a PhD degree.

For more info: Seo Lab: http://www.seoresearchlab.com/

How to Apply
Interested candidates should forward a cover letter describing research interests, a CV and names of three references to Dr. Young-Ah Seo at youngseo@umich.edu.

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イギリス、ロンドンにあるバーツがん研究所Claude Chelala教授グループで、データベース構築、遺伝子解析の研究者を募集しています。化粧品会社のシャネルパリと京都大学との共同研究でスキンケアなどに関するデータを扱います。通常、日本から海外就職ではビザ取得がネックとなりますが、この求人では研究所から英国就労許可のビザサポートが含まれますので、日本からの応募も大歓迎だそうです。日本からの応募ではスカイプでの面接になります。京都大学との共同研究であるので特に日本語と英語両方できる研究者を採用したいとのことです。

Senior Data Scientist/Bioinformatician - QMUL15054
Department: Barts Cancer Institute
Salary: £45,577 - £50,881 per annum (Grade 6)
Reference: QMUL15054
Closing date: 15-Jun-2018
Overview:
Applications are sought for a senior Data Scientist/Bioinformatician to join an international translational research programme in skin ageing using an integrated Omics-Environment-Lifestyle approach. The post will be based in the Bioinformatics Unit, Centre of Molecular Oncology, Barts Cancer Institute, within the Barts and The London School of Medicine and Dentistry, Queen Mary University of London. This project is in close collaboration with Chanel Beauty, Research and Innovation in France and the University of Kyoto in Japan.
The successful applicant for this post will analyse a unique cohort with over 20 years follow-up to translate data into actionable knowledge about skin aging. The successful candidate will build a health informatics/bioinformatics platform to enable -omics data analysis and integration with clinical attributes, behavioural medicine and epidemiology data. The proposed health informatics/bioinformatics platform could be the basis of a future model for community-based health promotion and monitoring.
Essential requirements for this post include a MSc and PhD degree in Computer Science/Data Science/Computational Biology/Bioinformatics or a relevant discipline, and substantial experience in relational database design and implementation. The successful applicant also needs to be proficient in -omics data analysis (at least three years’ experience in GWAS and/or NGS) as well as web application development. Experience of data management within a health environment and knowledge on contemporary data science technologies are desirable. Knowledge of French and Japanese languages will be an advantage. Programmatically this post requires expertise in relational database management systems including MySQL, scripting language including Perl, Python and R, and database-oriented web application development technologies. Experience of additional languages, e.g. Java or C, would be highly desirable. Familiarity with Linux network/server administration will be an advantage. Knowle!
dge of Research Governance, data Protection Act and Good Clinical Practice is highly desirable. The post-holder will be required to work flexibly with various members in the Bioinformatics team at the collaborating teams in Paris and Kyoto. A demonstrated ability to communicate well and working within a team are therefore essential.
The post is a fulltime, fixed-term position for 2 years. Starting salary will be in the Grade 6 range £45,577 - £50,881 per annum dependent on experience and inclusive of London Allowance. Benefits include 30 days annual leave, a defined benefit pension scheme and an interest free season ticket loan.
The Barts Cancer Institute requires that applicants invited for interview will need to provide all certificates to confirm their qualifications (specified in the Job Description).
Candidates must be able to demonstrate their eligibility to work in the UK in accordance with the Immigration, Asylum and Nationality Act 2006. Where required this may include entry clearance or continued leave to remain under the Points Based Immigration Scheme.
Barts Cancer Institute requires that applicants invited for interview will need to provide all certificates to confirm their qualifications (specified in the Job Description).
Informal enquiries about this post, including arrangements to visit the Institute/Centre, can be made to Professor Claude Chelala (c.chelala@qmul.ac.uk).
Details about Barts Cancer Institute can be found at www.bci.qmul.ac.uk.
Application enquiries can be directed to p.charles@qmul.ac.uk
To apply, please visit the Human Resources website on http://www.hr.qmul.ac.uk/vacancies and search for reference QMUL15054

The closing date is 15 June 2018 and interviews are likely to be held shortly thereafter.
Valuing Diversity & Committed to Equality

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