Description
A three year post-doctoral position is available in the laboratory of Jerome Dejardin to study the compensatory mechanisms at play during replicative and stress induced senescence. The laboratory is interested into the mechanisms driving changes in the control of heterochromatin organization during the senescence process and how this impacts gene expression.
The successful candidate will work in close collaboration with the groups of Giacomo Cavalli and Evi Soutoglou to tackle this important question. He/she will employ genomics and proteomics approaches to identify proteins involved in the formation of Senescence Associated Heterochromatin Foci (SAHF) and to map changes in genome architecture experienced by senescent cells (Hi-C and a novel conformation mapping approach developed in the lab).
The Institute of Human Genetics is located in Montpellier, France. This institute is one of the most renowned in France. Montpellier is located in the south, on the Mediterranean border and is ~3 hours away from Paris with the high speed train.

Qualifications
The candidate must hold a PhD degree or equivalent. A good knowledge in molecular biology and chromatin biochemistry is desirable. Experience in handling large datasets would be a plus. Excellent communication skills are essential.

Salary
Successful candidates will be offered competitive salary commensurate with experience and accomplishments.
Application details
Please apply by sending your CV and a motivation letter stating your research and career interests, together with the name of references to: Jerome Dejardin - jerome.dejardin@igh.cnrs.fr
Starting date: Spring 2017

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フランス、モンペリエにあるIGHのDejardin研究室ではポスドク研究員を募集しています。当研究室では、哺乳類におけるヘテロクロマチン構造形成機構の分子基盤について、生化学的な解析を軸に研究をしています。本募集では、老化細胞における特徴的なヘテロクロマチン構造体であるSAHFの研究を開始するにあたり、共同研究者と共に研究を遂行するポスドク研究員を募集します（期間３年間）。応募の詳細は、上記英文をご参照下さい。当研究室の過去の業績は当研究所のHPからご覧になれます（https://www.igh.cnrs.fr/EN/equipe-detail.php?id=62）。
研究内容についてより詳しく知りたい方は、直接PIであるDr.Dejardin (jerome.dejardin@igh.cnrs.fr) までお問い合わせ下さい。
その他基本的な質問であれば、当研究室のポスドクである西淵（gohei.nishibuchi@igh.cnrs.fr)　にお気軽にお問い合わせ下さい（日本語でも構いません）。