Two postdoctoral researcher positions for multiple years, supported by NIH and other non-federal grants, are immediately available in the Hiroyuki Nakai laboratory in the Department of Molecular and Medical Genetics, Oregon Health & Science University (OHSU). The Nakai lab studies adeno-associated virus (AAV) and its application for gene therapy using in vitro tissue culture models and in vivo models including mice, cats and non-human primates. In particular, the Nakai lab takes non-traditional multi-disciplinary approaches to study AAV viral proteins and virus-host interactions using the high-throughput next-generation sequencing (NGS) technology, barcoding, computer simulation and modeling, bioinformatics and biostatistics in addition to the traditional low-throughput structural and functional biology-based approaches, in collaboration with experts in each relevant field. In addition, the Nakai lab studies novel functions of assembly activating protein (AAP), a newly disco!
vered, non-structural AAV protein whose role appeared to be more than promoting capsid assembly. Ultimately, the lab will develop the next generation gene delivery vector systems that are more ideal for human gene therapy based on much deeper understanding of AAV than ever. By applying the new technologies that have been and will be developed in his lab, the Nakai lab tries to establish new approaches to treat diseases in the central nervous system (CNS), diabetes and genetic diseases and control reproduction in collaboration with investigators across and outside the university. In addition, the Nakai lab has had strong passion for addressing any unanswered questions in fundamental biological processes not directly relevant to AAV or gene therapy.

Salary: Starting at $42,840

Job Requirements:
PhD in a relevant field, MD, DVM or MD/PhD
Substantial knowledge and skills in molecular biology
Ability to perform multiple tasks at one time and prioritize them
Ability to organize and handle a large quantity of data
Strong enthusiasm for AAV and gene therapy research
［応募方法］下記書類を添付ファイルとして応募先e-mailアドレスに送って下さい。
(1) 履歴書（日本語または英語）
(2) 研究業績サマリーと当研究室で研究をするにあたっての抱負（Ａ４　１ないし2枚程度、 日本語または英語 ）
(3) 指導教官など、推薦状を英語または日本語で書いて頂ける推薦者２－3人の氏名と連絡方法

質問がごさいましたら、 下記応募先までお問い合わせください（日本語可）。

[応募先]　
Hiroyuki Nakai, M.D., Ph.D.
Associate Professor
Department of Molecular & Medical Genetics
Oregon Health & Science University School of Medicine
Associate Scientist
Division of Neuroscience
Oregon National Primate Research Center
Email: nakaih@ohsu.edu