ノースカロライナ大学チャペルヒル癌研究所医学生化学部門のDr. Greg Wangの研究室で２名あるいはそれ以上のポスドクを募集しています。私，辻 良明はノースカロライナ州立大学の研究者で、Dr.Wangとは研究領域で面識があり、今回依頼を受けて日本語で彼のラボのポスドク募集紹介をさせていただきます。Dr. Wangの研究室はクロマチンバイオロジーを活発に展開しており、具体的には、
１）新規のクロマチン結合／修飾タンパクの機能解析。
２）遺伝子改変マウスモデルを用いてヒストンメチレーション調節と造血系癌化メカニズムの解析。
３）正常細胞、癌細胞での遺伝子発現をエピジェノム（クロマチン修飾など）レベルで解析。
４）低分子RNAや最新のCRISPRテクノロジーを用いて新しい癌遺伝子、癌抑制遺伝子の同定。
応募していただいた方の経験は考慮するそうですが、これらの研究に興味とやる気のある方を特に希望するそうです。応募してみようと思われる方は履歴書と主論文pdf、それと３名の推薦者の連絡先を添えて Dr. Wangまでe-mailでお送りください。 gregwang.unc@gmail.com
Dr. Wangの研究室や彼の論文などはここを見てください。 http://www.med.unc.edu/biochem/wang
誠実で気鋭のこれからも益々期待される研究者だと思います。
投稿者：辻 良明

Postdoctoral Position of Gene Expression and/or Cancer Epigenetics
Job Description
UNC Lineberger Comprehensive Cancer Center and the Department of Biochemistry & Biophysics
University of North Carolina at Chapel Hill (UNC) School of Medicine

Multiple postdoctoral positions available for highly motivated candidates to join the group of Dr. Greg Wang (http://www.med.unc.edu/biochem/wang) at UNC Lineberger Comprehensive Cancer Center and the Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill (UNC) School of Medicine. With an emphasis on chromatin biology and cancer epigenetics, the group focuses on mechanistic understandings of how chromatin modifications define the epigenome, control gene expression and regulate cell proliferation versus differentiation of tissue-specific stem cells during development (especially hematopoietic system), and how their deregulations lead to oncogenesis. Multiple on-going projects include 1) biochemical characterization of several novel chromatin-associated factors/complexes, 2) knockout and knock-in mouse models with deficiency in histone methylation regulation in context of development and tumorigenesis, with a special focus on hematopoietic cancer !
and disease, 3) epigenomic and transcriptome analyses (ChIP-Seq and RNA-Seq) of normal versus cancer cells, 4) shRNA or CRISPR-based screening for novel oncogenes or tumor suppressors.

Applicants should be self-motivated with a strong background, laboratory and analytical skills, as well as a track record of publication. Previous experiences in aforementioned fields are welcome but not required. Full applications including CV, reprints of publications, and contact information of three referees should be submitted to e-mail: gregwang.unc@gmail.com