11 PhD Positions in Neuroscience

The University of Lübeck is recruiting highly motivated doctoral researchers for a structured three-year PhD programme within the newly established

DFG Research Training Group 1957 Adipocyte-Brain-Crosstalk.

The programme will start as of May 1st, 2014.

In an interdisciplinary research approach the Research Training Group GRK 1957 focuses on the effects of hormones derived from adipose tissue (adipokines) on CNS function and, in turn, the control of adipose tissue and body weight by the brain. Cellular and molecular techniques as well as animal models and clinical studies will be used to address emerging questions within this context.

The participating institutions at the University of Lübeck are:
- Department of Internal Medicine I
- Department of Neurology
- Department of Psychiatry and Psychotherapy
- Institute for Experimental and Clinical Pharmacology and Toxicology

Participants in the programme will be trained in molecular endocrinology and translational medicine of adipose tissue function. Besides their doctoral research projects, the PhD researchers will obtain additional qualifications through laboratory and soft-skill courses, lectures, seminars, and summer schools. A major feature of this programme is an internship of the doctoral researchers in the laboratory of international expert collaborators for up to three months. For more information on the research projects see www.grk1957.uni-luebeck.de.

11 PhD positions for doctoral researchers are offered. The salary is in accordance with the German public service salary scale (TV-L E13 65%).

Applications are welcome from candidates with an excellent graduation (Master or equivalent) in life sciences (e.g. biology, pharmacology, neurosciences, psychology) and an active interest in the indicated research field. The programme is taught in English which requires very good written and spoken English skills. Interested candidates should fill in the application form at www.grk1957.uni-luebeck.de. Deadline for applications is February 12th, 2014.

Suitable candidates will be invited to attend a recruitment day in Lübeck on March 5th, 2014 to give short presentations of their recent research project and interviews for final decisions.

The University of Lübeck is committed to support gender equality, women are explicitly encouraged to apply. Further information on the University of Lübeck can be found under www.uni-luebeck.de.

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Postdoctoral Position in Gut Physiology : Geneva, Switzerland

An exciting postdoctoral position is available at the Medical Faculty, University of Geneva. University of Geneva offers a world leading, highly stimulatory intellectual environment for cutting-edge metabolic research. The main interests of our lab are the molecular mechanisms underlining metabolic diseases, primarily obesity and insulin resistance, and in particular the roles of the adipose tissue and the gut in the regulation of metabolism. Projects involve using state-of-art technologies and in vivo animal models, generally aiming at developing strategies for treatment of dyslipidemia, diabetes and obesity.

Candidates with techinical expertise in intestine from leading labs are particularly encouraged to apply.

Geneva offers an outstanding environment for study and research in a beautiful natural setting. Successful candidates will work in an ambitious, multidisciplinary translational research group led by Prof. Mirko Trajkovski, and will include national and international collaborations.

How to apply
Please send a cover letter stating your previous research experience, CV and contact information for three references as a single file to: Mirko.Trajkovski@unige.ch

Please note that the post will remain open until the position is filled….

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Postdoctoral Position Open in the Dasgupta Lab: The long term research goal of our lab is to understand the metabolic and novel non metabolic functions of the energy sensor AMP Kinase in embryonic neural stem cells, brain development and in adult neural stem cell function. I am looking for a dedicated, energetic and ambitious person with a background in Neuroscience and some experience and aptitude in mouse genetics. Experience in making knockout and knockin mouse models will be highly advantageous. Knowledge of basic molecular biology and biochemistry is necessary. Some knowledge in cell culture, flow cytometry, microscopy, immunohistochemistry, biochemical assays and cell signaling is desirable. Persons with their own fellowships may also apply.

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Baylor University Medical Centerの Gastrointestinal Cancer Research Labでポスドクをしております奥川と申します。現在、自分のボスであるDr.Ajay Goelが、ポスドクを募集しております。当研究室は、消化器癌（特に大腸癌）におけるgenetic, epigeneticな変化を、様々な臨床サンプルを用いて解析し、新規バイオマーカーの確立とそのメカニズムの解明を目指しているところです。日本人もポスドクメンバーに多く在籍しているほか、論文発表を行う機会も多く得られるところです。また米国テキサス州のダラスは米国南部の有数都市で気候も温暖であり、Baylor University Medical Centerはその中心部に位置し、交通の便がよく生活にも便利な場所です。Baylor University Medical Centerに併設されるBaylor Research Instituteでは最新の研究設備が整備されております。詳細は下記をご覧いただき、ご興味のある方はご連絡頂ければと存じます。

Postdoctoral Fellowship: Gastrointestinal Cancer Genetics and Epigenetics
A postdoctoral position is available for immediate recruitment for a highly motivated candidate to join a team of researchers at the Baylor Research Institute and Sammons Cancer Center, Baylor University Medical Center, Dallas, TX, USA. The laboratory headed by Drs. Ajay Goel. Ph.D. and C. Richard Boland, M.D. focuses on understanding the interplay between genetic and epigenetic alterations in gastrointestinal cancers, with particular emphasis on colorectal cancer.

This position involves studies surrounding work in the fast developing field of genetic and epigenetics research. More specifically, the projects will involve;

a) Exploration of the role of DNA methylation, histone modifications and non-coding RNAs (miRNA, LncRNAs, SnoRNAs etc.) in gastrointestinal cancer biology
b) Establishment of innovative methodologies for the development, screening and validation of epigenetic and non-coding RNA biomarkers for the earlier diagnosis, prognosis and prediction of gastrointestinal neoplasia
c) Use of high-throughput microarray and Next Generation sequencing technologies for the identification of DNA methylation and non-coding RNA biomarkers.

An ideal candidate should have a Ph.D. or a M.D. degree with a strong background in biochemistry and molecular biology, and relevant experience in cancer genetics and epigenetics. The candidate with prior hands-on experience in state-of-the-art methods such as Next Generation Sequencing (genomic, RRBS/MeDip and RNASeq etc), array-based methylome/ miRNA/ gene expression analysis, bisulfite pyrosequencing, methylation specific real-time PCRs and microRNA work will be considered an important strength.

Knowledge and experience with various bioinformatic and statistical data analysis tools will be highly preferred. The candidate must possess excellent writing and communication skills, a solid record of peer-reviewed publications, commitment to drive scientific projects, motivation for independent research and ability to deliver on agreed objectives.

The position is available for 2-3 years with the potential for extension. Salary is commensurate with experience. Interested candidates should submit a cover letter, curriculum vitae, a description of their research experience and career goals, along with names of three references via email to:

Ajay Goel, Ph.D
Gastrointestinal Cancer Research Laboratory
Baylor University Medical Center
3500 Gaston Avenue, Suite H-250
Dallas, TX 75246
E-mail: ajay.goel@baylorhealth.edu and

Yoshinaga Okugawa, M.D.
Gastrointestinal Cancer Research Laboratory
Baylor University Medical Center
3500 Gaston Avenue, Suite H-250
Dallas, TX 75246
E-mail: yoshinaga.okugawa@baylorhealth.edu

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Postdoc Position Available
Department of Pediatrics
Pediatric Research Center
The University of Texas Medical School at Houston
Houston, TX

We are seeking a highly motivated, organized and enthusiastic postdoctoral fellow to study embryonic kidney development and its relationship to kidney pathologies, including cystic kidney diseases (including ciliopathies) and cancer. We are interested in the role of Wnt signaling and primary cilia in shaping nephric tubules, utilizing Xenopus (frog) embryos and mammalian tissue culture as models. Current goals include: 1) Determining how PCP components affect tubule and cilia formation; 2) Discovering novel components affecting nephron development; 3) Visualizing in vivo tube formation using advanced live imaging techniques; 4) Generating transgenic animals to visualize nephrogenesis in vivo

Current projects utilize developmental, molecular and cell biological approaches including imaging in living embryos. Applicants with a Ph.D., M.D. or equivalent and a strong background in Developmental Biology, Embryology, Cell Biology, Molecular Biology and/or Stem Cell Biology are highly encouraged to apply. Salary and benefits are commensurate with relevant experience. Review of applications will continue until the position has been filled.

Please send your CV, cover letter indicating current and future research interests, and the name/email address of three references to:

Rachel K. Miller, Ph.D.
Department of Pediatrics
The University of Texas Medical School at Houston
6431 Fannin Street, MSE R316
Houston, Texas 77030
Email: Rachel.K.Miller@uth.tmc.edu

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POSTDOCTORAL POSITION

INSTITUTE OF HUMAN GENETICS (CNRS)
MONTPELLIER, France

A postdoctoral position is available to study the regulation of DNA damage and replication checkpoints using Xenopus egg extracts and mammalian cells as model systems.

Highly motivated candidates with a recent Ph.D., or equivalent, and a strong background in biochemistry and/or cell and molecular biology are encouraged to apply. Montpellier is an international and scientifically dynamic city located in the south of France, which is very well connected to Paris and other European cities.

Applications must state the name of at least two referees and can be sent by email (domenico.maiorano@igh.cnrs.fr

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POST DOCTORAL POSITION IN DNA REPLICATION

A position is available to study the regulation of initiation of DNA
replication.

The research projects of our laboratory are focused on DNA replication origins
from metazoans, their characteristics, and the regulation of their activation. Our
model systems include cell cultures from mouse and human cells, as well as invitro
DNA replication systems from Xenopus eggs.

Our projects aim at understanding the nature of replication origins and
characterizing new factors regulating initiation of DNA replication.

The Institute of Human Genetics (www.igh.cnrs.fr) is a modern large CNRS
Institute located in the University and Hospital area in Montpellier. The working
language is English. Fully endowed with state of the art scientific equipment,
the IGH generates an excellent scientific environment for high quality and
intensive scientific life. The city is one of the most lively and concentrated areas
for research scientists in France.

We would be glad to receive applications from motivated scientists with a
strong expertise in molecular biology and / or protein biochemistry. The position
is for at least two years.

Please submit a curriculum vitae and contact information of 2-3 referees to
Marcel Méchali, Institute of Human Genetics, CNRS, 141 rue de la Cardonille,
34396 Montpellier Cedex 5

Tel: 33 (0) 434 359 917

e-mail: mechali@igh.cnrs.fr
web: www.igh.cnrs.fr./equip/mechali/

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