My laboratory has two major research interests: 1) investigation of molecular mechanisms underlying glioblastoma multiforme cancer stem cell behavior and 2) identification of novel signaling pathways controlling brain development.

 I am particularly focused on ubiquitin-proteasome system-specific mechanisms for both projects.

Washington University School of Medicine consistently ranks in the top 5 medical schools in the U.S.A. and is home to many of the United States' top scientists and physicians. The Department of Neurological Surgery in particular has a rich tradition of clinical and scientific excellence and is highly collaborative with other Departments in the medical center.

MD or PhD with expertise in molecular biology and biochemistry with a preference for new graduates or postdoctoral fellows with 2 or fewer 
years of experience.

Salary and benefits are based upon NIH 2012 guidelines
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-12-033.html

 and departmental guidelines. For full benefits including health, please see website
http://medschoolhr.wustl.edu/



Documents required for application

1) CV

2) 3 letters of recommendation and contact information for these references



Due date for application

May 1, 2013

Starting date for job
Summer 2013 with at least 2 year commitment



References



A.H. Kim, H. Yano, H. Cho, D. Meyer, B. Monks, B. Margolis, M.J.
Birnbaum, and M.V. Chao. Akt1 regulates a JNK scaffold during
excitotoxic apoptosis. Neuron 35(4): 697-709. 2002.



A.H. Kim and A. Bonni. Thinking within the D box: Initial 
identification of Cdh1-APC substrates in the nervous system. Mol Cell 
Neurosci. 34(3): 281-7. 2007.



A.H. Kim, S.V. Puram, P.M. Bilimoria, S. Keough, M. Wong, D. Rowitch,
and A. Bonni. A centrosomal Cdc20-APC pathway controls dendrite
 morphogenesis in postmitotic neurons. Cell 136(2):322-336. 2009.



Y. Yang, A.H. Kim, T. Yamada, B. Wu, P.M. Bilimoria, Y. Ikeuchi, N. de
la Iglesia, J. Shen, and A. Bonni. A Cdc20-APC ubiquitin signaling
 pathway regulates presynaptic differentiation. Science 326:575-8.
2009.



S.V. Puram, A.H. Kim, Y. Ikeuchi, A. Riccio, S. Koirala, J.T.
Wilson-Grady, A. Merdes, S.P. Gygi, G. Corfas, and A. Bonni. A Unique
 CaMKIIβ Signaling Pathway at the Centrosome Regulates Dendrite 
Patterning in the Mammalian Brain. Nat Neurosci 14(8):973-83. 2011.



Albert H. Kim, MD, PhD

Assistant Professor of Neurosurgery, Neurology, and Developmental Biology

Washington University School of Medicine

660 S Euclid Ave, Box 8057

St. Louis, MO 63110

Tel: 314-362-8443 
Fax: 314-362-2107

kima@wudosis.wustl.edu