Two Postdoctoral Fellow positions are currently available in the Lefebvre laboratory in the Department of Cellular and Molecular Medicine at the Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA (http://www.lerner.ccf.org/cmm/lefebvre/).

The goals of the available research projects are to elucidate molecular mechanisms driving cell fate and function in the skeleton. These projects are aimed at providing new, important insights into mechanisms that contribute to normal skeleton development and adult homeostasis, and that are deregulated in skeletal dysplasias and adult degeneration diseases. The unifying theme of projects in the laboratory is the regulation and mode of action of Sox transcription factors and their upstream regulators and downstream targets in the skeleton. The realization of these projects will involve state-of-the-art approaches in cell and molecular biology, genomics and proteomics, and mouse genetic models.

Successful candidates will demonstrate dedication to pursue a research career in the skeleton field. The candidates will have a Ph.D. in molecular biology, genetics, developmental or cell biology, with a scientific focus on a skeleton-related topic, and will have several first-author publications in top-tier, peer-reviewed journals.

The Lerner Research Institute and Department of Cellular and Molecular Medicine provide a prosperous and resourceful environment for biomedical research, with state-of-the-art facilities and competitive salaries, and participate in multiple programs for pre- and post-doctoral trainees. As an equal opportunity and affirmative action employer, the Cleveland Clinic recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives, and backgrounds.

To apply, please email your curriculum vitae, contact information for three references, and an essay describing research expertise and career goals to Véronique Lefebvre, PhD (lefebvv@ccf.org).