Job description:
A postdoctoral position is available in the laboratory of Hiroko Yano, PhD at Washington University School of Medicine to study molecular mechanisms of neurodegenerative diseases, starting in the spring 2013. Transcriptional dysregulation and mitochondrial dysfunction are thought to contribute to the pathogenesis of neurodegenerative diseases including Huntington’s disease (HD). We are trying to understand how these key cellular changes lead to neuronal death and dysfunction as well as to identify the upstream pathways that regulate these changes. We use molecular biological, cell biological, biochemical, and genetic approaches and take advantage of primary neuron culture as well as cell and animal models of HD. A current major focus is the identification of novel epigenetic pathways that alter histone modifications and lead to aberrant gene expression in HD.

Washington University School of Medicine consistently ranks in the top 5 medical schools in the USA and is home to many of the United States' top scientists and physicians. The Department of Neurological Surgery in particular has a rich tradition of clinical and scientific excellence and is highly collaborative with other Departments in the medical center.

Link to Websites:
http://wustl.edu/
http://medicine.wustl.edu/
https://hopecenter.wustl.edu/
http://www.neurosurgery.wustl.edu/

Qualifications:
Candidates should hold PhD or MD with expertise in molecular and cell biology and biochemistry with a preference for new graduates or postdoctoral fellows with 3 or fewer years of experience. We seek highly motivated individuals who ideally have experience in the field of gene regulation and epigenetics.

Materials needed to send:
Interested candidates should send a short personal statement including their research interests and background, CV, and contact information for three references to: yanoh@wudosis.wustl.edu

Hiroko Yano, PhD
Assistant Professor of Neurosurgery and Neurology
Washington University School of Medicine
660 S Euclid Ave, Box 8057
St. Louis, MO 63110
yanoh@wudosis.wustl.edu (日本語可)