Postdoctoral Fellow in Structural Biology of Innate Immune Recognition

A postdoctoral fellow position is available at the Structural Immunobiology Unit (SIBU), Laboratory of Immunology, NIAID/NIH for a highly motivated individual to study the molecular mechanisms of innate immune recognition. Our research program is composed of two integrated themes: the mechanisms of nucleic acid recognition by innate immune receptors and the study of large macromolecular signaling platforms known as the “inflammasomes.” We use X-ray crystallography as the primary method to dissect the molecular details of innate receptors and signaling adapters, integrated with chemical tools that target these signaling pathways for potential therapeutic applications.

SIBU is well funded with state-of-the-art equipment for molecular biology, protein chemistry and crystallography, including participation in dedicated synchrotron beam time allocation. There are numerous opportunities for collaboration and acquiring new skills at NIH with one of the leading scientific communities dedicated to structural biology and immunology research.

We are seeking future career scientists capable of independent thinking and interested in learning new techniques. The ideal candidate must have a M.D. or Ph.D. degree with less than five years of postdoctoral experience. Strong skills in protein expression, purification and molecular biology are essential. Knowledge in protein crystallization and X-ray crystallography is highly desirable. The candidate must possess excellent written and oral communication skills, and will be expected to work in a diverse and collaborative environment.

Salary will be competitive and commensurate with experience, supplemented with excellent fringe benefits.

To apply, please e-mail a CV, bibliography, and cover letter with a brief description of research experience and interests, and three reference letters to: T. Sam Xiao, Ph.D., xiaot@niaid.nih.gov

T. Sam Xiao, Ph.D.
Chief, Structural Immunobiology Unit
Laboratory of Immunology
National Institute of Allergy and Infectious Diseases
National Institutes of Health
Building 4, Room 228B
4 Memorial Drive
Bethesda, MD 20892-0430, USA
Phone: 301-402-9782, FAX: 301-480-1291, E-mail: xiaot@niaid.nih.gov
http://www.niaid.nih.gov/labsandresources/labs/aboutlabs/li/structuralimmunobiology/Pages/Xiao.aspx