私の所属する研究室（Prof. Bernd Groner Lab、ゲオルクシュパイヤー化学療法研究所、フランクフルト、ドイツ）で、修士課程修了以上の学歴を有する研究者の募集を行っております。特に東日本大震災の影響で博士課程を断念した方などを優先的に採用したいとの理由で、こちらのサイトに投稿させていただきました。

研究内容は乳腺の発生および乳癌です。特に幹細胞生物学、エピジェネティクスに興味があり、基本的な分子生物学の手技を習得されている方、英語でのコミュニケーションができる方が望ましいとのことです。実際の研究指導は研究室のポスドク、Dr. Vafaizadehが担当します。募集要綱は以下の通りですが、さらに質問がある方はDr. Vafaizader (V.Vafaizadeh@med.uni-frankfurt.de) までお問い合わせ下さい。

PhD Position in Molecular Biology/Biochemistry

A PhD student position is available from July 2011 initially for a period of 2 years in the lab of Prof. Dr. Bernd Groner in the Georg-Speyer-Haus Institute for Biomedical Research in Frankfurt am Main / Germany. Mammary gland development is dependent on the self-renewal of multipotent mammary stem cells and the specification and maintenance of cell fates in the progenitor cells. This occurs through the activation of gene regulatory networks, which are composed of hierarchical sets of transcriptional activators and repressors. Genetic and epigenetic changes in mammary stem cells or in descendant luminal and basal progenitor cells may account for the origins of different subtypes of breast cancer. We have established an in vivo model system by orthotopic transplantation of gene-modified mammary stem cells into recipient mice. The consequences of the genetic and epigenetic changes on the normal and tumorigenic development of glands can be studied. Using this model we were able to generate some mammary tumor models resemble e.g. the ER+PR+ luminal subtype in human breast cancer by the expression of constitutively activated variant of transcription factor Stat5 in mammary stem cells and progenitors. The project is mainly focused on the genetic and epigenetic characterization of these tumor cells and will be supervised by Dr. Vida Vafaizadeh.

Highly motivated candidates holding a Master degree (or equivalent) in biology or biochemistry or a related field with a strong background in cellular and molecular biology are welcome to apply. Previous expertise in the chromatin and epigenetic field and FACS analysis is a plus and command of English is necessary. Please send your application (including CV, letter of motivation name and address of two referees) by e-mail to: 
V.Vafaizadeh@med.uni-frankfurt.de

Dr. Vida Vafaizadeh
Institute for Biomedical Research Georg-Speyer-Haus
Paul-Ehrlich-Strasse 42-44
D-60596 Frankfurt / Main 
Germany
Telephone: +49/(0)69-63395-254