Joslin Diabetes Center
Postdoctoral Position – Beta Cell Regeneration
Rohit N. Kulkarni MD PhD

Postdoctoral position available immediately to work on beta cell regeneration using mouse models and cell biology approaches.

We utilize cell and molecular biological, genetic and genomic approaches to dissect and define cellular and molecular mechanisms that underlie beta cell regeneration and apoptosis. Particular interests include exploring the role of the growth factor and leptin signaling pathways in the replication of beta and alpha cells. (Nat Genet 38:583, 2006; PNAS 104:8977, 2007; JCI 117:2860, 2007). Current projects are aimed at creating and phenotyping novel mouse models with a focus on proteins that are involved in beta/alpha cell cycle control and molecular signals governing pancreatic islet cell growth.

Seeking qualified individual interested in dissecting the mechanisms of beta/alpha cell regeneration using mouse and human islets and beta cells. Successful candidate will have strong background in molecular biology, biochemistry, and endocrinology. Prior experience with creating transgenics, ES cell culture, mouse handling and microscopy essential.

Send brief statement of research interests, CV, and names of three references to:
Lindsay.huse@joslin.harvard.edu