Postdoctoral Fellow
Neurodegenerative disease
Medical College of Georgia

Applications are now being accepted for a postdoctoral fellow position to study the role of molecular chaperones and protein aggregation in neurodegenerative diseases. The Medical College of Georgia is a premier research university located in Augusta, Georgia.

Applicants must have a Ph.D. degree from an accredited university. Experience in molecular biology, protein biochemistry/biophysics, mammalian cell culture methods, familiarity with mouse models and histology in the area of neurodegeneration are required. Competency is expected in using MS Office, Endnote, Adobe Photoshop and web-based tools. Highly motivated individuals with creative problem solving capabilities and paying attention to detail are preferred. Ability to work independently as well as in a cooperative manner to develop, organize and complete research projects is expected.

To apply, please send (i) your curriculum vitae; (ii) a cover letter describing research accomplishments and interests; (iii) the names and addresses of three references familiar with your professional skills and background to: acashikar@mcg.edu and in addition please apply online at www.mcg.edu/Jobs for position #6658. AA/EEO/Equal Access/ADA Employer

リンク用URL

本求人は候補者が決定したため募集を打ち切りました。This advertisement was withdrawn because the position has been filled.

ペンシルバニア大学病理学部Tykocinski/Tone Labでポスドクを募集しています。

高等細胞の免疫系は、T細胞、B細胞，樹状細胞(dendritic cell, DC)等の免疫細胞により、抗原の提示、細胞表層リセプターを介した細胞間のコミニュケイション等により巧妙に制御されています。当研究室では、免疫制御物質ならびに 細胞表層リセプター等の詳細な研究を行い、そのリコンビナントプロテイン或いは改良型プロテインを作成し、それにより免疫系を正、負両方向にコントロールし，癌ならびに自己免疫疾患等の治療に貢献する事を目的としております。３年程前、英国のオックスフォード大学で制御性T細胞（Treg）、DCの活性を制御するサイトカイン、TNFならびにTNFリセプターファミリー(GITR, GITR ligand, CD40等)の研究を行っていた研究グループを新たに加え Treg細胞の分化、それらの遺伝子発現調節機構の解明へとその研究の幅を広げ、更にT細胞ならびに抗原提示細胞(DC等)を介した免疫系の活性化機構の解明、治療への応用へと発展させる事を考えております。

今回、こちらの研究者の帰国、移動に伴いポスドクのポジションに空きが出来ます。研究には、癌ならびに自己免疫疾患のモデルマウスを使用する事もありますので、マウスを用いた研究の経験者は歓迎されますが、やる気のある方であればこちらで技術を習得する事も可能です。
当研究室は、Dr. Tykocinski(Department Chair)とDr. Tone(Assistant Professor)との共同運営となります。興味のある方は、ytone@mail.med.upenn.eduまでご連絡ください。

Yukiko Tone
Pathology and Laboratory Medicine
University of Pennsylvania
412 Stellar-Chance
422 Curie Blvd., Philadelphia
PA, 19104-6100

215-573-5999 (ask Yuki)

リンク用URL

本求人は候補者が決定したため募集を打ち切りました。This advertisement was withdrawn because the position has been filled.

Research postdoc fellowship stipend is immediately available for a highly motivated candidate with strong interests in mucosal immunology and molecular cell biology at the Division of Gastroenterology & Hepatology (PD Dr. Elke Cario), University Hospital of Essen, Germany. Research in this laboratory is focussed on functional characterization of innate immune signaling pathways (mainly Toll-like receptors) and intestinal epithelial responses in acute and chronic inflammation of the gastrointestinal mucosa (including inflammatory bowel diseases). Publications relevant for this project include: Gastroenterology. 2004 Jul;127(1):224-38; J Immunol. 2006 Apr 1;176(7):4258-66; Gut. 2005 Aug;54(8):1182-93; Infect Immun. 2000 Dec;68(12):7010-7. Individuals applying for this position must have a Ph.D. and/or M.D. degree and should be fluent in English and/or German (both verbal and written) and display excellent interpersonal skills and ability to work with others. Solid practical ex!
perience in basic molecular cell biology and immunology techniques is essential. The position is initially for one year and can be prolonged after positive evaluation. Remuneration will be on a tax-free, monthly stipend basis (without insurance support) according to the regulations of the University of Duisburg-Essen. Low-cost accommodation is available on campus. Interested candidates are invited to submit their application (preferably as one file – including cover letter, detailed curriculum vitae, 2-page statement of research experience and interests as well as name/address of at least three references) electronically to email: elke.cario@uni-due.de

PD Dr. med. Elke Cario
University Hospital of Essen
Division of Gastroenterology & Hepatology
Institutsgruppe I
Virchowstr. 171
D-45147 Essen
Germany

Applicants will be reviewed until the position is filled.

リンク用URL

ハーバード大学医学部・CBR Institute for Biomedical Research (http://cbr.med.harvard.edu/)では、研究所の拡張にともない、３名の tenure track Assistant Professorを以下のように米国内外より募集します。
興味のある方はFrederick W. Alt、または日本語で島岡までお問い合わせください。

Frederick W. Alt, Ph.D.
Scientific Director/Search Committee
CBR Institute for Biomedical Research
200 Longwood Avenue, Boston, MA 02115
CBRI-recruitment@cbrinstitute.org

OR

Motomu Shimaoka, M.D., Ph.D.
Search Committee
The CBR Institute for Biomedical Resarch
200 Longwood Avenue, Boston, MA 02115
shimaoka@cbrinstitute.org
617-278-3272

(As seen in the 17 November issue of Science)
Assistant Professor Positions
Harvard Medical School
CBR Institute for Biomedical Research
As part of CBRI's Longwood Consolidation and a new building project to be completed in mid 2008, we are recruiting tenure track faculty at the rank of Assistant Professor in partnership with the Department of Biological Chemistry and Molecular Pharmacology (BCMP) and the Department of Pathology at Harvard Medical School (HMS). CBRI is highly interactive and offers outstanding opportunities for collaboration and technical support in areas such as imaging. Successful candidates will direct independent research laboratories at CBRI, and their work will complement and enhance the efforts of our distinguished faculty in immunology, inflammation, vascular biology, infectious disease and cancer
Structural Biology - BCMP and CBRI

We are seeking candidates who integrate macromolecular structure and biological function, especially those working on fundamental problems involving signal transmission in extracellular and cytoplasmic environments and across cell membranes. Approaches using molecular dynamics and spectroscopy, protein structure prediction and design, X-ray crystallography and innovative light microscopy will be of special interest. The new structural biology initiative at CBRI will be able to draw on available resources such as the HMS Center for Molecular and Cellular Dynamics (CMCD)

Molecular Immunology/Stem Cell Biology - Pathology and CBRI

We are seeking candidates performing cutting-edge research in immunology or related disciplines using the immune system as a model to understand fundamental mechanisms in cellular or organismal biology. Areas of focus include cellular signaling, transcriptional regulation, cellular differentiation, development of organ systems, stem cell function, adaptive and innate immunity including NK cell biology, infectious diseases, cancer genetics and immunology, mathematical modeling of cellular processes using approaches spanning biochemistry and molecular biology, innovative microscopy and mouse genetics

Vascular Biology - Pathology and CBRI

We are seeking candidates in the broad area of endothelial/blood vessel development and function in health and disease. Areas of focus include vasculogenesis and angiogenesis, thrombosis, studies of specialized blood beds and the blood brain barrier, endothelial junctions and regulation of vascular permeability, tumor vasculature, vascular cell matrix interactions, vascular remodeling and genetic determinants of vascular disease

Please forward cover letter requesting consideration by one of the three search committees, curriculum vitae, reprints of key publications, three reference letters, and a two-page statement of research interests including previous contributions and future research plans, no later than January 30, 2007 to: Frederick W. Alt, Scientific Director/Search Committee, CBR Institute for Biomedical Research, 200 Longwood Avenue, Boston, MA 02115, CBRI-recruitment@cbrinstitute.org

CBRI and Harvard Medical School are Affirmative Action/Equal Opportunity Employers. Women and minority candidates are strongly encouraged to apply

リンク用URL

Boston Medical Schoolにてポスドクを新たに募集しています。
PIはJianlin Gongでdendritic cellとcancerのfusion cell vaccineを初めてNat.Medに報告した人です。
研究内容はDCと癌細胞との融合細胞を用いた癌免疫ワクチンの基礎的、臨床的研究です。
御興味のある方はshigeo_koido@hotmail.comまで御連絡ください。

リンク用URL

ポスドク募集
ワシントン大学医学部(アメリカ合衆国ミズーリ州セントルイス)
School of Medicine, Washington University in St.Louis
http://www.wustl.edu/

ワシントン大学Hsieh LabではDr.Hsiehが見出した白血病病因分子であるMLL1/2を切断する唯一のプロテアーゼ分子”Taspase-1”の新規標的分子の探索及びその作用メカニズムの解析に従事するポスドクを募集中です。これまでの研究背景は特に問いませんが生化学的手法に明るい方は特に歓迎です。

研究室はハーバード大学Korsmeyer研究室から独立したDr.James Hsieh（Taspase-1/MLLグループ）とDr.Emily Cheng（アポトーシスグループ）の夫妻で共同運営されています。Hsiehグループでは遺伝子改変マウスから培養細胞まで様々なレベルでTaspase1及びMLL1/2の機能解析を行っています。基本的には一人1-2テーマを独立に担当します。セミナーなどは2グループ合同で行っており、実験室・居室も共通で使用しています。2人のPIはともにRO1他複数のグラントでサポートされており、研究機器なども充実していています。研究室構成は現在PI2名、テクニシャン2名、ポスドク3名（日本人1名）、学生4名（日本人1名）です。

<参考文献>
Takeda S et al., Genes & Development 20, 2397-409 (2006).
Zhou H et al., MCB 26, 2728-2735 (2005).
Hsieh JJ et al., Cell 115, 293-303 (2003).
Hsieh JJ et al., MCB 23, 186-194 (2003).

興味をもたれた方はDr. Hsiehまでご連絡ください。正式な応募はコンタクト後で構いません。また、ちょっと話を聞いてみたいという方は笹川宛に連絡いただいても構いません。

Hsieh James MD, PhD.
Assistant Professor
Division of Oncology
Campus Box 8069
Washington University Medical School
660 South Euclid Avenue
St. Louis, MO 63110, USA
Tel: +1-314-362-9115
e-mail: jhsieh@im.wustl.edu（英語）
http://hematology.im.wustl.edu/faculty/hsieh/hsieh.html

笹川覚　PhD.
+1-314-362-1508(Lab)
ssasagaw@im.wustl.edu（日本語可）

リンク用URL

ポスドク募集 (MD, PhD or MD/PhD)

テンプル大学医学部心臓血管研究センター (Philadelphia, PA)

９月に行った募集は採用がすでに決定しましたが、今回、来年一月以降の一名の増員を急募いたします。
当研究室は細胞生物学、分子生物学およびタンパク工学（プロテオミックス）を主体とした手法を用いて心血管系の情報伝達と機能解析を中心に現在、以下のテーマで研究を行っています(NIH-RO1 funded from NIH HLBI)。
1. アンジオテンシン受容体の新しい情報伝達とその機能解析
2. 血管系でのインスリン抵抗性の意義
3. NOと活性酸素を介した細胞内情報伝達
4. Rho/Rho kinaseの新しい機能解析

ニュヨーク、ワシントンは車で2時間のフィラデルフィアは日本人には生活しやすいところでしょう。留学にあたっては私と日本人のポスドク（現在５名の日本人スタッフ）が生活面、研究面共に懇切丁寧に面倒を見ます。ご興味を持った方は履歴書（学歴と研究歴／業績、日本語可）を以下にe- mail してください。（分野は問いませんが研究実績のある方を希望します。）

給与 $37000/year、家族を含む医療保険完備、休祭日は大学の規定に準じる。

連絡先

Satoru Eguchi, MD. PhD. FAHA
Associate Professor of Physiology and Cardiovascular Research Center
Temple University School of Medicine
e-mail: 以下のリンクを参照のこと。（日本語可)

最近の当研究室の文献 (Selected from 91 English Publications)
Arterioscler Thromb Vasc Biol 26:e133. 2006, Am J Physiol (invited review) 291:C1-C10. 2006, Hypertension (editorial) 47:339. 2006, J Biol Chem 280:26592. 2005, Arterioscler Thromb Vasc Biol 25:1831. 2005, Mol Cell Biol 23: 1581. 2003, Hypertension 41:775. 2003, J Biol Chem 277:44695. 2002, Mol Endocrinol 16: 367. 2002, Circulation 106:909-912, 2002, J. Biol. Chem., 276: 7957. 2001.

教室紹介 http://www.temple.edu/medicine/faculty/e/eguchis.htm

リンク用URL

Postdoctoral Fellow in Neurodegenerative disease
Medical College of Georgia

Applications are now being accepted for a postdoctoral fellow position to study the role of molecular chaperones and protein aggregation in neurodegenerative diseases. The Medical College of Georgia is a premier research university located in Augusta, Georgia.

Applicants must have a Ph.D. degree from an accredited university. Experience in molecular biology, protein biochemistry/biophysics and mammalian cell/tissue culture methods are required. Familiarity with mouse models and histology in the area of neurodegeneration are a plus. Excellent oral and written communication skills in English are essential. Competency is expected in using MS Office, Endnote, Adobe Photoshop and web-based tools. Highly motivated individuals with creative problem solving capabilities and paying attention to detail are preferred. Ability to work independently as well as in a cooperative manner with the supervisor to develop, organize and complete research projects is expected.

To apply, please send (i) your curriculum vitae; (ii) a cover letter describing research accomplishments and interests; (iii) the names and addresses of three references familiar with your professional skills and background to: acashikar@mcg.edu and in addition please apply online at www.mcg.edu/Jobs for position #6658. AA/EEO/Equal Access/ADA Employer

リンク用URL

Postdoctoral Fellow Position in Structural Biology of Innate Immune Response

A postdoctoral fellow position is immediately available in the Structural Immunobiology section, Laboratory of Immunology (NIAID/NIH) for a highly motivated individual with a strong interest in signaling mechanisms of the innate immune responses. The innate immune system serves as the gatekeeper and coordinator for the defense against microbe infections. One of the paradox of the innate immune receptors is that they are specific for each class of pathogen antigens, whereas not too stringent to render them non-responsive to similar but different epitopes. How do the receptors achieve such “broad” specificity is among the most important questions structural biologists could strive to answer. The projects aim to elucidate how the pattern recognition receptors (PRRs) sense pathogenic epitopes and how this recognition initiates downstream signaling cascades to direct appropriate responses against various pathogens. One of the best approaches to decipher the signalin!
g network is through studying protein-protein interactions involved in the crosstalk, using X-ray crystallography integrated into other biophysical and biochemical techniques. Elucidating the signaling mechanisms in innate immune response has important implications in the prevention and treatment of infectious diseases, autoimmune diseases and cancer.

The lab will be primarily structure oriented, complemented with functional studies. The section is fully funded and equipped with state-of-the-art protein expression, purification and crystallization instruments. There is regularly scheduled beam time slot for NIH at the APS synchrotron for data collection. There are also numerous opportunities for collaboration and acquiring new skills among the 27 Institutes and Centers at NIH with one of the most diverse groups of international researchers.

The ideal candidate must have a Ph.D. in biochemistry/biophysics/X-ray crystallography or a related field, and extensive experience in molecular biology and protein expression/purification. Knowledge in crystallization, data collection, phasing, model building and refinement, and structure analysis is desirable but not required. The candidate must possess excellent writing and oral communication skills, and will be expected to work in a diverse and collaborative environment. Salary will be highly competitive and commensurate with experience and in the $40,000 range, supplemented with excellent fringe benefits.

For inquiries, please contact:

Tsan Xiao, Ph.D.
Chief, Structural Immunobiology Section
Laboratory of Immunology
National Institute of Allergy and Infectious Diseases
National Institutes of Health
Building 4, Room 138
4 Center Drive
Bethesda, MD 20892 USA
Phone: 301-594-2096
FAX: 301-480-1291
E-mail: xiaot@niaid.nih.gov

リンク用URL

A postdoctoral position is available to study the transcriptional control of energy metabolism and metabolic diseases in our laboratory at University of Massachusetts Medical School, Worcester. Worcester is about 40 miles west of Boston and is the third largest city in New England area. Our research particularly focuses on the physiological roles of the PPAR subfamily of nuclear receptors, their mechanism of action, and their regulation by transcriptional co-factors. Please visit http://www.umassmed.edu/pgfe/faculty/wang.cfm for additional information. Candidates should have a Ph.D. and/or M.D and possess research experience in molecular biology or animal physiology.

Please forward your CV to:
Dr. Yong-Xu Wang
Program in Gene Function and Expression
Program in Molecular Medicine
University of Massachusetts Medical School
Worcester, MA 01605
Email: yongxu.wang@umassmed.edu

リンク用URL

武田薬品工業（株）キャリア採用募集--応募締切2006年11月17日(金)日本時間厳守--

武田薬品工業（株）では薬理系研究職の募集を行います。
詳細は、バイオインフォデザインーキャリアプランニングプログラム
（http://www.bid-cpp.com）のウェブサイトでご確認下さい。

■ 募集職種と応募資格
　募集職種　薬理系研究職(グループリーダーおよび一般研究職)
　応募資格　修士卒以上
　　　　　　　研究グループ(5〜10名)においてリーダーシップを発揮できる方、
　　　　　　　または将来グループリー ダーとして期待できる方。
　年齢　　　グループリーダー(博士号保持者)は40歳位まで、一般研究者は35歳位まで。

■ 職務内容 (医薬研究本部における 創薬研究)
　1 中枢神経研究者
　2 生活習慣病領域研究者
　3 骨関節疾患研究者
　4 ガン領域研究者
　5 病態モデル動物の樹立・作製に優れた研究者
　6 ペプチド医薬研究者

■ 応募方法
1)提出書類
・ 履歴書(所定の様式・日本語)
・ 研究概要(メインの研究について→A4縦5枚以内・日本語・及び公表論文)
・ 転職理由(A4縦1枚程度・日本語)
2)応募締切
2006年11月17日(金)日本時間 厳守
3)応募方法
下記メールアドレスまで1)で指定の書類を提出ください。
4)面接
提出いただいた書類を審査させていただき、合格された方はCPP2006@Bethesda(2006/12/1〜3)の会場にて面接(1次面接)させていただきます。
5)費用負担
1次面接者には交通費の一部を負担させていただきます(領収書をお持ちください)。
・東部 US$100 ・中部 US$200 ・西部 US$300

応募に関する問い合わせ先
　〒532-8686 大阪市淀川区十三本町二丁目17番85号
　武田薬品工業株式会社 医薬研究本部 医薬業務部 人材開発グループ
　キャリアプランニングプログラム (担当:藤澤)
　TEL 06-6300-6722
　E-mail fujisawa_miho@takeda.co.jp

弊社についての詳しい情報は武田薬品ホームページをご覧ください。
　URL http://www.takeda.co.jp/

リンク用URL

POSTDOCTORAL POSITION

The laboratory of Dr. Fawaz George Haj at the Department of Nutrition, University of California, Davis is seeking outstanding candidates for a postdoctoral position. Applications are sought from highly motivated individuals with an M.D. or Ph.D. in Life Sciences. Experience in molecular biology, mouse models of obesity/diabetes and/or cell culture is highly desirable.

Projects involve using already available knockout mouse models and specialized cells to address the role of protein-tyrosine phosphatases and their interacting partners in insulin signaling, obesity and diabetes. Representative work: Fawaz Haj, et.al. 2002, Science, 295 (5560): 1708-11, and Fawaz Haj, et.al. 2005, Journal of Biological Chemistry, 280 (15): 15038-46. State-of-the-art facilities are available on Campus, with possibility of collaboration with laboratories in Boston and the Max Planck Institute (Germany).

Application Procedure: Send a cover letter addressing your interest in this position, a copy of your Curriculum Vitae, and names and complete contact information of three references to fhaj@bidmc.harvard.edu. Apply before February 15, 2007 for full consideration, although applications will proceed until suitable candidates are identified.

リンク用URL