Weill Medical College of Cornell University　ポスドク募集

私の友人でCornell大学のassociate professorをしているDr. Pengbo Zhou
がpostdocを募集しております。以下の求人にご興味のある方は直接、Dr. Zhouにお問い合わせください。よろしくお願いいたします。
勝二郁夫（国立感染症研究所ウイルス第二部）

Weill Medical College of Cornell University
-Postdoctoral Research Associate positions

Postdoctoral Research Associate positions available immediately to study the ubiquitin-dependent proteolysis in controlling hematopoiesis and DNA repair,and the associated tumorigenic processes, and to explore the applications of a novel protein knockout technology. Please refer to the lab website
http://www.med.cornell.edu/research/pez2001/.

Experiences in the following two areas are preferred:

(1) Mouse models (transgenic and/or knockout mice). Applicants with
experiences in mouse genetics, histology, immunohistochemisry, and
hematology are preferred.

(2) Protein expression, purification, and enzymatic analysis. Applicants
familiar with general protein purification procedures, which include
ion-exchange chromatography, gel filtration, affinity chromatography, and FPLC, are desirable.

Publications

Chen, X., Zhang, Y., Douglas, L. and Zhou, P. (2001) UV-damaged DNA-binding proteins are targets of CUL-4A-mediated ubiquitination and degradation. J.Biol. Chem. 276, 48175-48182.

Zhang, Y., Morrone, G., Zhang, J., Chen, X., Lu, X., Ma, L., Moore, M., and Zhou, P. (2003) CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein. EMBO J. 22, 6057-6067.

Zhang J., Zheng, N. and Zhou, P. (2003) Exploring the functional
complexity of cellular proteins by protein knockout. Proc. Natl. Acad. Sci.USA 100, 14127-14132.

Cong, F., Zhang, J., Pao, W., Zhou, P., and Varmus, H. (2003) A protein knockdown strategy to study the function of b-catenin in tumorigenesis. BMC Mol. Biol. 4:10.

Craig Cohen, J., Scott, D., Miller, J., Zhang, J., Zhou, P., and Larson,J.E. (2004) Transient In Utero Knockout (TIUKO) of C-MYC affects late lung and intestines development. BMC Dev. Biol. 4:4.

Zhou, P. (2005) Targeted protein degradation. Curr. Opin. Chem. Biol. 9,51-55.

Zhang, J. and Zhou, P. (2005) Ectopic targeting of substrates to the
ubiquitin pathway. Methods Enzymol. 399, 823-833.

Li, T., Chen, X., Garbutt, K. C., Zhou, P., and Zheng, N. (2006) Crystal Structure of DDB1 In Complex with Simian Virus 5 V Protein: Viral Hijack of A Propeller Cluster in Ubiquitin Ligase. Cell 124(1), 105-117.

Zhou, P. (2006) REGr: a shortcut to destruction. Cell 124(2), 256-257.

Cornell University will sponsor the H1B visa if required.
Send curriculum vitae and references to:

Dr. Pengbo Zhou
Associate Professor
Department of Pathology and Experimental Medicine
Weill Medical College of Cornell University
1300 York Ave., C417
New York, NY 10021

E-mail: pez2001@ med.cornell.edu