A postdoctoral position is available immediately to study cellular and molecular basis of cancer focusing on the PI3K/PTEN signaling pathway. Specifically, the molecular mechanism of mTOR activation by the small GTPase Rheb will be studied. Projects include identification and characterization of Rheb interacting partners, determination of the subcellular localization of the mTOR signaling complexes and understanding of mTOR substrate specificity. Our laboratory is located within the premier Canadian cancer research institute with state-of-the-art facilities hosting over 400 basic and clinical researchers. Highly motivated candidates with a Ph.D. and/or M.D. and experience in biochemistry, molecular and cell biology should email their curriculum vitae and names of three references to:

Vuk Stambolic, Ph. D.
Scientist,
Division of Signaling Biology
Ontario Cancer Institute, University Health Network and
Assistant Professor, Dept. of Medical Biophysics,
University of Toronto and
Canada Research Chair in Cellular Signaling
610 University Avenue, Room 10-123
Toronto, Ontario, M5G 2M9
Canada
vuks@uhnres.utoronto.ca
tel. 416-946-2961
fax. 416-946-2984