POSTDOCTORAL RESEARCH FELLOWS
VASCULAR DEVELOPMENT LABORATORY
CANCER RESEARCH UK LONDON RESEARCH INSTITUTE

Blood vessels play many essential roles in vertebrate organisms and are also directly involved in a range of disease conditions such as cancer. We are studying the signalling processes controlling blood vessel morphogenesis and, in particular, the interactions between the different cell types forming the vessel wall. This work involves genetic tissue-specific and inducible gain-of-function and loss-of-function studies in mice. To address the underlying molecular mechanisms, we also employ a wide range of other techniques such as immunohistochemistry, confocal/time-lapse microscopy, cell/tissue culture, biochemistry and molecular biology. We are particularly interested in the function of Eph/ephrin molecules, Notch signalling, pathways controlling cell adhesion and motility as well novel regulators of the angiogenic programme.
During the last five years, research from the Vascular Development Laboratory has been published in leading journals such as Nature, Nature Genetics, Cell and Developmental Cell.
More information can be found under the following link:
http://science.cancerresearchuk.org/research/loc/london/lifch/adamsr/

We invite applications by enthusiastic and committed prospective postdoctoral fellows who wish to join our expanding research team and work on one of the research subjects mentioned above.
Postdoctoral training fellowships, tenable for three years with the option of further extension, are available during 2006. Starting salaries for fellows are in the range of ￡22,250 - ￡32,000 (depending on experience).
Please send your applications, which should in include your CV, a short summary of your current research and research interests and the names of the referees for reference letters, to Dr Ralf Adams (ralf.adams@cancer.org.uk), Vascular Development Laboratory
CANCER RESEARCH UK London Research Institute, 44 Lincoln’s Inn Fields, London WC2A 3PX, United Kingdom.

The London Research Institute (LRI) is one of the leading European research laboratories and based right in the centre of London. The LRI houses almost 50 research groups and provides outstanding central research support facilities, which include FACS, bioinformatics, mass spectrometry and proteomics, protein and peptide synthesis, electron and light microscopy, DNA sequence analysis, DNA microarrays, histopathology and the production of genetically modified mice.